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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM48
All Species:
18.79
Human Site:
S321
Identified Species:
41.33
UniProt:
Q9BTX1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9BTX1
NP_060557.2
674
76305
S321
C
L
P
K
V
L
N
S
N
P
P
P
I
I
K
Chimpanzee
Pan troglodytes
XP_513417
776
87618
S423
C
L
P
K
V
L
N
S
N
P
P
P
I
I
K
Rhesus Macaque
Macaca mulatta
XP_001091911
530
59703
F185
Y
S
Y
S
L
L
Y
F
V
N
N
M
N
Y
L
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8VCB1
673
75391
S322
C
L
P
K
V
L
N
S
N
P
P
R
I
V
K
Rat
Rattus norvegicus
Q6AXN4
673
75694
S322
C
L
P
K
V
L
N
S
N
P
P
L
I
I
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518195
431
47121
V84
R
P
G
A
S
A
A
V
T
L
T
P
P
S
V
Chicken
Gallus gallus
XP_001235442
684
77153
S332
C
L
P
K
I
L
N
S
N
P
P
L
I
I
K
Frog
Xenopus laevis
Q6AX31
660
74320
V315
N
S
N
T
L
P
L
V
K
Y
L
A
M
Q
D
Zebra Danio
Brachydanio rerio
Q7SZC5
671
74423
K318
E
K
S
T
L
V
M
K
F
L
A
L
Q
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VCG4
578
65368
M233
S
H
I
L
S
V
D
M
D
E
R
L
D
G
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784037
756
85199
T410
T
S
F
Y
S
T
A
T
S
P
G
P
H
Q
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86
76.4
N.A.
N.A.
87
86.9
N.A.
20.4
67.8
56.8
53.5
N.A.
22.7
N.A.
N.A.
28.1
Protein Similarity:
100
86.2
77.3
N.A.
N.A.
92.1
92.5
N.A.
33.5
79.3
72.4
72.2
N.A.
43.4
N.A.
N.A.
45.3
P-Site Identity:
100
100
6.6
N.A.
N.A.
86.6
93.3
N.A.
6.6
86.6
0
0
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
100
13.3
N.A.
N.A.
93.3
93.3
N.A.
6.6
93.3
13.3
13.3
N.A.
20
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
10
19
0
0
0
10
10
0
0
0
% A
% Cys:
46
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
10
0
0
0
10
10
10
% D
% Glu:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
10
10
0
0
0
0
0
10
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
10
0
0
10
0
% G
% His:
0
10
0
0
0
0
0
0
0
0
0
0
10
0
0
% H
% Ile:
0
0
10
0
10
0
0
0
0
0
0
0
46
37
0
% I
% Lys:
0
10
0
46
0
0
0
10
10
0
0
0
0
0
46
% K
% Leu:
0
46
0
10
28
55
10
0
0
19
10
37
0
0
19
% L
% Met:
0
0
0
0
0
0
10
10
0
0
0
10
10
0
0
% M
% Asn:
10
0
10
0
0
0
46
0
46
10
10
0
10
0
0
% N
% Pro:
0
10
46
0
0
10
0
0
0
55
46
37
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
19
0
% Q
% Arg:
10
0
0
0
0
0
0
0
0
0
10
10
0
0
10
% R
% Ser:
10
28
10
10
28
0
0
46
10
0
0
0
0
10
0
% S
% Thr:
10
0
0
19
0
10
0
10
10
0
10
0
0
0
0
% T
% Val:
0
0
0
0
37
19
0
19
10
0
0
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
10
10
0
0
10
0
0
10
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _